Introduction

After a seven-month hiatus, college football is back with the 2025 season kicking off this weekend. While Week 0 offers a smaller slate of games compared to Week 1, it still provides some intriguing betting opportunities. Here, we delve into two key matchups that stand out for early bettors.

Iowa State vs. Kansas State: OVER 49.5

Location: Dublin, Ireland

Key Insights:

• Kansas State's Running Game: Last season, Kansas State ranked second nationally in yards per rush attempt. Players like Dylan Edwards and Avery Johnson bring explosive potential to the ground game.
• Iowa State's Defense: The Cyclones struggled against the run last season, ranking 84th in rushing success rate. With a new-look defensive line, they might find it challenging to contain Kansas State.
• Iowa State's Passing Attack: Rocco Becht, now in his third year as a starter, could exploit Kansas State's rebuilt secondary, which allowed the sixth-most passing yards in the Big 12 last season.

Prediction: Expect a high-scoring game with both teams capitalizing on their strengths. The OVER 49.5 is a solid bet.

Sam Houston +10 at Western Kentucky

Key Insights:

• Sam Houston's Defense: Last season, the Bearkats were 15th in total defense and ninth against the pass. This strength aligns well against a Western Kentucky team that relies heavily on its passing game.
• Western Kentucky's Offense: The Hilltoppers are breaking in a new quarterback without their top three receivers from last season. This new unit may struggle to replicate previous success.
• Western Kentucky's Defense: Historically weak, ranking 96th nationally in total defense and 129th against the run. This could be a significant issue against Sam Houston's strong rushing attack led by QB Hunter Watson.

Prediction: Sam Houston catching double digits seems inflated. The Bearkats have a solid identity and should keep this game close.

Conclusion

Week 0 may not offer the abundance of games that Week 1 does, but it still presents valuable betting opportunities. Focusing on matchups like Iowa State vs. Kansas State and Sam Houston vs. Western Kentucky can provide early-season success for savvy bettors.