Mayer vs. Ryan 2: Fight Analysis, Expert Predictions, and Betting Odds for the Explosive Welterweight Rematch

Breaking down the strategy, strengths and expert predictions for the high-stakes Mayer-Ryan rematch with betting insights for the ESPN+ main event.

The Rivalry Continues: Mayer vs. Ryan Rematch Preview

The boxing world eagerly anticipates the ESPN+ main event this Saturday night as WBO welterweight champion Mikaela Mayer (20-2, 5 KOs) defends her title against bitter rival Sandy Ryan (7-2-1, 3 KOs) in a highly anticipated rematch of their September 2024 classic that saw Mayer win by razor-thin majority decision (97-93, 96-94, 95-95).

Fight Night Details

  • Date/Time: Saturday, March 29 @ 10 PM ET (ESPN/ESPN+)
  • Prelims Start: 7 PM ET (ESPN+)
  • Venue: Madison Square Garden, New York
  • Tale of the Tape: Fighter Age Height Reach Stance Record
    Mayer 34 5'9" 66.5" Orthodox 20-2 (5 KOs)
    Ryan 31 5'8½" 67.5" Orthodox 7-2-1 (3 KOs)

The Controversial First Encounter

Their September bout produced fireworks both in and out of the ring:

  • Ryan was splattered with red paint while leaving her hotel pre-fight (allegedly by Mayer's camp)
  • Trainer drama as Kay Koroma switched from Mayer to Ryan before the first fight
  • 186-185 total punches landed (Mayer edged by just one punch)
  • Mayer landed 39 power body shots (10 more than Ryan)

Expert Breakdown: Hall of Famer Al Bernstein's Analysis

Keys to Victory:

For Mayer:

  • Control distance with jab & footwork
  • Maintain volume punching advantage
  • Avoid being trapped on ropes
  • Win early rounds decisively

For Ryan:

  • Start faster than first fight
  • Cut off the ring effectively
  • Focus on body attack
  • Score cleaner, more visible punches for judges

"This is a true 50-50 fight," Bernstein noted. "Mayer's movement and combinations versus Ryan's power and physicality. That first fight was 2024's Fight of the Year candidate - I expect nothing less this time."

Former Champion EC's Inside Perspective

Former two-division champ Erica Anabella Farias (fought both women) reveals:

  • Mayer's timing and late-round surges will be crucial
  • Ryan must control emotions and stick to gameplan
  • Judges favor Mayer's cleaner, more technical work
  • Predicts Mayer by decision in another close contest

"When Mayer smells blood, she turns up the pressure brilliantly," Farias observed. "Ryan hits harder but wastes energy when frustrated. That's the champion's advantage."

Betting Insights (via ESPN's Ian Parker)

Market Odds
Mayer Win -105
Ryan Win -115
Goes Distance -210

Recommended Bets:

  • Mayer by decision (+160)
  • Fight goes over 9.5 rounds (-150)
  • Ryan to win rounds 1-3 (+120)

"At these odds," Parker noted, "Mayer presents value. Her championship experience and ring generalship should prove decisive over 10 rounds."

Co-Main Event Preview: Zepeda vs. Farmer II

The Cancun lightweight showdown features:

  • Zepeda (-750 favorite) defending WBA title
  • Farmer looking to avenge split decision loss
  • Parker's pick: Over 10.5 rounds (-170)

How to Watch

Full card airs live on ESPN/ESPN+ starting at 7 PM ET with the main event expected around 10 PM ET. International viewers can stream via ESPN Player.

What to Read Next

Jai Opetaia Dominates Claudio Squeo, Sets Sights on Gilberto Ramírez for Cruiserweight Unification
Boxing

Jai Opetaia Dominates Claudio Squeo, Sets Sights on Gilberto Ramírez for Cruiserweight Unification

Jai Opetaia successfully defends his IBF and The Ring world championships, calls out Gilberto Ramírez for a cruiserweight unification bout.

Keyshawn Davis' Chaotic Night: Backstage Brawl After Brother's Defeat
Boxing

Keyshawn Davis' Chaotic Night: Backstage Brawl After Brother's Defeat

Keyshawn Davis' tumultuous week culminated in a backstage altercation following his brother's loss to Nahir Albright, adding drama to an already chaotic boxing event.

Keyshawn Davis vs. Edwin De Los Santos Fight Cancelled Due to Weight Miss: What Happened and What's Next
Boxing

Keyshawn Davis vs. Edwin De Los Santos Fight Cancelled Due to Weight Miss: What Happened and What's Next

Keyshawn Davis' fight against Edwin De Los Santos was cancelled after Davis missed weight by 4.3 pounds, leading to the WBO title being stripped and negotiations failing.

The Legacy of Vasyl Lomachenko: A Father's Vision and a Fighter's Ambition
Boxing

The Legacy of Vasyl Lomachenko: A Father's Vision and a Fighter's Ambition

Explore the rigorous training and unique father-son dynamic that shaped Vasyl Lomachenko into a boxing legend.

Vasiliy Lomachenko: The Unyielding Spirit of a Boxing Legend Amidst War
Boxing

Vasiliy Lomachenko: The Unyielding Spirit of a Boxing Legend Amidst War

Discover how Vasiliy Lomachenko's boxing career and dreams persevere through the turmoil of the Ukraine war, as he continues his quest for the undisputed lightweight title.

Fabio Wardley's Dual Challenge: Battling Justis Huni and Embracing Fatherhood
Boxing

Fabio Wardley's Dual Challenge: Battling Justis Huni and Embracing Fatherhood

Fabio Wardley faces a pivotal fight against Justis Huni while preparing to become a father, showcasing his resilience and focus.

Ginjiro Shigeoka's Boxing Career Ends After Emergency Brain Surgery
Boxing

Ginjiro Shigeoka's Boxing Career Ends After Emergency Brain Surgery

Former IBF strawweight champion Ginjiro Shigeoka retires after emergency brain surgery following a split decision loss to Pedro Taduran.

Charlo vs. Plant: The Ultimate Showdown or Canelo's Next Challenge?
Boxing

Charlo vs. Plant: The Ultimate Showdown or Canelo's Next Challenge?

Explore the intense rivalry between Jermall Charlo and Caleb Plant, their recent fights, and the potential for a showdown with Canelo Alvarez.

Charlo vs. Plant: The Road to a Blockbuster Boxing Showdown
Boxing

Charlo vs. Plant: The Road to a Blockbuster Boxing Showdown

Jermall Charlo and Caleb Plant prepare for pivotal fights, setting the stage for a potential blockbuster showdown in the super middleweight division.

Jaime Munguia Faces Potential Suspension After Positive Drug Test Post-Victory Over Bruno Surace
Boxing

Jaime Munguia Faces Potential Suspension After Positive Drug Test Post-Victory Over Bruno Surace

Jaime Munguia's recent victory over Bruno Surace is under threat after testing positive for a banned substance, potentially leading to a suspension.

Anthony Joshua's Comeback: One Fight Only in 2025, Fury or Wilder on the Horizon?
Boxing

Anthony Joshua's Comeback: One Fight Only in 2025, Fury or Wilder on the Horizon?

Anthony Joshua, recovering from elbow surgery, plans only one fight in 2025. Promoter Eddie Hearn hints at potential matchups with Tyson Fury or Deontay Wilder.

Boxing Showdowns 2025: Top Fights, Upsets, and the Next P4P King
Boxing

Boxing Showdowns 2025: Top Fights, Upsets, and the Next P4P King

Explore the most anticipated boxing matches of 2025, including Canelo vs. Crawford, Usyk vs. Dubois rematch, and Taylor vs. Serrano trilogy. Discover potential upsets and the next pound-for-pound king.

Holly Holm Returns to Boxing: A Legendary Comeback Against Yolanda Vega
Boxing

Holly Holm Returns to Boxing: A Legendary Comeback Against Yolanda Vega

Former UFC champion Holly Holm makes a thrilling return to boxing after 12 years, facing undefeated Yolanda Vega in a high-stakes match under Most Valuable Promotions.

Chris Eubank Jr. and Frank Warren Resolve Legal Dispute Amicably: A New Chapter in Boxing
Boxing

Chris Eubank Jr. and Frank Warren Resolve Legal Dispute Amicably: A New Chapter in Boxing

Chris Eubank Jr. and promoter Frank Warren have amicably settled their defamation lawsuit, paving the way for a positive future in boxing.

Sam Goodman Eyes World Title Shot After Dominant Victory Over Cesar Vaca
Boxing

Sam Goodman Eyes World Title Shot After Dominant Victory Over Cesar Vaca

Australian boxer Sam Goodman revives his career with a unanimous points win over Cesar Vaca, eyeing a world title shot against Naoya Inoue.

Load More

We use essential cookies to make our site work. With your consent, we may also use non-essential cookies to improve user experience and analyze website traffic. By clicking "Accept," you agree to our website's cookie use as described in our Cookie Policy.